MK-2866 AKA Ostarine.

What is Ostarine?

Also known as MK-2866, Ostarine is a Selective Androgen Receptor Modulator (SARM) developed by GTx with the aim of treating and preventing muscle wasting. MK-2866 can potentially become a medical prescription for people suffering with the condition of Cachexia, Sarcopenia and Atrophy. It can also be a used in Testosterone Replacement Therapy. Ostarine, when chemically defined, belongs to the SARM class i.e. it generates selective anabolic activity. It is preferred over the usual anabolic steroids as it does not contribute to androgenic activity in the non-skeletal muscle tissue. MK-2866 is most effective in the maintenance of lean body mass.  MK-2866 is patented by GTX.

How does Ostarine work?

MK-2866 is an SARM which means it works by binding to the androgen receptor and demonstrating bone and muscular anabolic activity. The binding of Androgen Receptor alters the expression of genes and subsequently leads to the increase of protein synthesis which is responsible for muscle buildup. In simpler words, SARM of the kind MK-2866 lead to the same muscle growth as is stimulated by steroids but unlike steroids, it does not have effects on prostrate and sexual organs. In fact, Ostarine specifically concentrates its effects on muscle tissue. This is one of the prime reasons why it is immensely potent for athletes and body builders. It is also viewed as a potential agent for minimizing atrophy when recovering from serious surgery.

What are some uses of MK-2866?

  1. Cutting

MK-2866 primarily helps in losing body fat. It fits perfectly into the protocols for maintaining appropriate muscle mass while you are on the journey of shedding calories. The reduction in calories is usually accompanied by loss of muscle tissue but Ostarine because of its anabolic effects helps in cutting calories without letting go of the hard-earned muscle mass.

Dosage: A 15-20 mg of Ostarine dosage shall be good for losing body fat without having to undergo any considerable side effects.

  1. Bulking

Ostarine, or MK-2866, is the most active and the most anabolic member of the SARMs which means that it is a perfect agent for the gain of lean muscle. It has been found that the lean mass gained with the help of Ostarine is prompt and keep able. Some users have experienced a gain of up to 7lbs through a cycle of 8 weeks in which 25mgs of MK-2866 were consumed. This is also the most common dosage of Ostarine for bulking. The gains acquired through Ostarine are entirely lean muscle.

  1. Recomping

This is perhaps the area which triggers the popularity of Ostarine. Most body builders look for a recomping effect while the loss of fat and gain of muscle continues. Ostarine shines in the recomping effect owing to its high nutrient partitioning benefit. Many users have been found to report that the consumption of Ostarine at maintenance levels helps in producing weight loss while gaining muscle mass and strength. Ostarine is usually consumed orally but has no toxic effect on the liver and/or the blood pressure of an individual. This is the prime reason as to why MK-2866 has prolonged effects as compared to other steroids.

Dosage: The usual dosage protocol of Ostarine for Recomping is 20-25 mg over a period of 6 to 8 weeks. In addition to this, the diet of an individual must also be optimized in terms of calories and proteins.

  1. Injury Prevention

Since Ostarine demonstrate bone and muscular anabolic activities, it can potentially be used for rehabilitating the injuries particularly those related to tendon and bones.

Dosage: For injury prevention, Ostarine must be consumed every day in the quantity of 12.5 mg. Effective results should appear after 6 to 8 days.

What are the timings of MK-2866 dosages?

MK-2866 is one of the very few substances that offer a convenient consumption cycle. Ostrine has been found to have a half life of around 24 hours which means that it only needs to be taken once a day.

How is Ostarine better than other Steroids?

  1. Ostarine is non-methylated which means that it is non-toxic and has no toxic effects on the liver or the blood pressure. Its oral bioavailability is less toxic as compared to other steroids.
  2. It does not require a large off-time in between dosage cycles. A normal cycle runs for 4 to 6 weeks and a user is supposed to wait a maximum of 10 weeks between two consequent cycles.
  3. Induces a great sense of well being independent of any aggression which impacts the users’ daily life positively.
  4. Doses above 25mg may have some suppression and may run longer than 4 weeks but the stringent PCT are not necessary.

How is Ostarine better than other SARMs?

  1. Unlike S4, Ostarine is independent of any androgenic properties in the non-muscle tissue.
  2. Ostarine is also free of the metabolite M1 which is responsible for toxicity of S4.

The Bottom Line

Ostarine is:

  • Good for strength
  • Good for lean mass gains
  • Good for endurance—both aerobic and anaerobic
  • Joint healing abilities
  • Anabolic even at low doses (3 mg)
  • Half life of circa 24 hours

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