Citrin® K and GarCitrin® are extracted from the fruit of the plant Garcinia cambogia, which has a long history of use in Indian foods (mostly as an acidulant). The bioactive ingredients of this fruit are hydroxycitric acid (HCA), a derivative of citric acid, the agent that gives citrus fruits their characteristic tart flavor, and Garcinol. Clinical studies have shown that upon Citrin consumption, there is a modest decrease in body weight and suppression of appetite. This happens through two mechanisms, namely, inhibition of fatty acid synthesis and stimulation of fatty acid oxidation (ß oxidation). GarCitrin® contains both HCA and Garcinol. Garcinol makes GarCitrin® more effective than Citrin® by modulating regulatory cell signal pathways and, therefore, facilitating the uptake of HCA into the cells.