Ibutamoren (MK-677)


Ibutamoren, also known as MK-677, is one of the most powerful and useful SARMS on the market. For those not familiar with the term, SARMs are selective androgen receptor modulators. These drugs are able to engage only with the androgen receptors in the muscle. This makes them extremely beneficial and in some cases better than steroids, because steroids engage with androgen receptors in bones, skin and internal organs. This can result in various side effects, whereas SARMs can usually be used without experiencing any side effects. This selectiveness makes their anabolic to androgenic ratio approximately 10:1, whereas the ratio in standard injectable testosterone is 1:1. Because of this SARMs are able to produce a better anabolic reaction without the androgenic side effects such as gynecomastia, bloating, high blood pressure etc.

My current recommendation for MK-677 is Paradigm Peptides.


People who stumble upon SARMs, like Ostarine, LGD 4033 or Ligandrol, or YK11,  are generally skeptical, because it seems to good to be true. Well, it’s easy to test and see for yourself, or check out the forums with countless testimonials acknowledging their effectiveness The only downside is that SARMs are not as powerful as regular anabolic steroids. If you’re looking to become a mass monster, then by all means take the most powerful steroids like Anadrol 50, Dianabol, Deca Durabolin, Trenbolone, etc. These will turn you into a mass monster. But SARMs are the best choice for those looking to gain high quality, lean muscle mass in a relatively natural way. One can expect to gain 10-15 pounds of lean muscle within a matter of one cycle (usually 4-5 weeks). Not to mention the cutting benefits, which are in some cases even more impressive.

This was just a small introduction in order for you to understand in which category Ibutamoren belongs. But this compound is truly special and stands out from the standard SARMs in a very interesting way.


Ibutamoren is a SARM but it’s also an oral growth hormone secretagogue. That’s a mouthful. What it basically means is that it gives chemical signals to the pituitary gland to produce more growth hormone. There are a few other products that are able to perform in the same way, such as Ipamorelin and GHRP-6, but these drugs need to be injected regularly to have an effect, plus they have a variety of side effects. Ibutamoren is void of all the negative side effects associated with these products, and is easily administered through oral use.

It was first produced in order to help patients with muscle wasting conditions such as HIV, and also to help children and elders who suffer from hormonal deficiencies. In order to make it available to as many patients as possible, Ibutamoren is actually relatively cheap, considering the desirable effects it can produce. Just like so many other drugs of similar nature, it was picked up by the bodybuilding and professional athlete crowd and it became popular within these circles in a very short amount of time. To actually be able to increase natural growth hormone production is basically a dream come true. Growth hormone has such a wide range of positive benefits that we would have to mention every single organ in our body and physique characteristics to actually give it the proper credit. But if we were to focus only on athletic performance and bodybuilding purposes, growth hormone is responsible for producing muscle, shedding body fat, proper utilization of nutrients, bone density, healthy skin complexion, endurance and energy. To be able to increase HGH it is usually necessary to inject HGH daily, and the whole process is very expensive and unpractical. But the benefits are amazing. The cast of the movie Expandables has made quite a comeback in the action-movie genre basically through the use of growth hormone. How else could Sylvester Stallone look 30 years younger and be in better shape than guys half his age? Sure, it takes dedication in the gym and a proper diet, but the hormones and overall musculature of a 65 year old person cannot withstand rigorous exercise regime without a hormonal boost and the revitalizing effects of growth hormone. And trust me, these guys are able to get the top notch stuff. So, it’s quite obvious that HGH is very important for our bodies to be at optimal performance. The fact that an easily available product like Ibutamoren can raise HGH levels naturally is one of the most important scientific achievements that has the ability to transform the fitness industry as a whole.


Ibutamoren works through 4 mechanisms:

  • Increases GHRH, the growth hormone releasing hormone
  • Reduces somastotatin (a hormone that lowers GH release)
  • Amplifies GHRH signals in the pituitary gland
  • Inhibits somatostain receptor signals

Taking as little as 5 mg daily of Ibutamoren showed an increase of growth hormone levels. There were in fact two scientific studies done that showed the benefits of taking this SARM. In the first study a young man who suffered from a muscle wasting disease was given 25 mg of Ibutamoren daily. In seven days, he showed a remarkable improvement in IGF-1 and GH levels, and his muscle wasting condition was alleviated for as long as the daily dosages continued.

Another study was used in order to determine whether this drug would actually help in building muscle mass without gaining fat as well. Subjects were taking 25 mg of Ibutamoren for 8 weeks. Researchers observed heightened metabolic rate as well as an increase in HGH, IGF-1 and a better protein utilization. There were also some health benefits observed, most notably an increase in bone density. Growth hormone is already known to be beneficial for faster recovery after sports injuries. What occured out of this whole experiment was significant muscle gains with an actual lowering of bodyfat, which can be observed in professional bodybuilders when preparing for contests, as they actually gain muscle while getting shredded a few months before stepping on the stage.


So to cap off the main benefits from the bodybuilding perspective here is a bit more detailed information:

  1. Muscle Building – Ibutamoren can increase muscle mass while at the same time keeping the bodyfat under control. This can be especially helpful when bulking during the off season.
  2. Increased Endurance and Energy – If you’re trying to do longer weighlifting sessions, improve your cardio, wake up refreshed and earlier while having enough energy throughout the day Ibutamoren can help in achieveing these results. Being able to perform longer and harder in the gym is another practical way to achieve better results, regardless of the chemical boost gained through the direct chemical impact on muscle building and metabolism
  3. Fat Loss – Losing excess body fat is easy with Ibutamoren. This is true regardless of your current shape. Whether you’re obese and trying to get lean, or you’re a professional bodybuilder or fitness competitor that wants to prepare for contest shape, and be under 10% bodyfat, the same mechanisms will help you achieve those goals without much trouble. A good diet and training routine are of course important, but increased HGH levels by themselves aid in proper utilization of calories, which means that basically all the food you intake will be properly distributed in the muscle rather than stored as fat.
  4. Overall Health – Increased HGH not only aids in athletic performance, but also positively shifts our emotional state and sleeping patterns. If you feel depressed, anxious or lack confidence, these are often the symptoms of low testosterone and improper secretion of growth hormone. An increase of these hormones leads to a more assertive and confident approach to everday challenges. A bit of aggression is a good thing, if channeled into proper, life improving activities.


To use MK-677 is very simple and easy, because it’s an oral supplement and there aren’t any complicated protocols involved. It can be taken for for an extended period of time, up to 10 weeks. A moderate daily dose is 25 mg. Some experienced lifters use doses of 50 mg and higher. This is however, not necessary if you’re using  the supplement for the first time. Adjusting the dose during the cycle is also allowed. If you feel that the dose you’re currently taking is not strong enough to produce the results you expect, you can increase it a bit and see whether it has a stronger effect. And vice-versa, perhaps you can get the same results by taking a lower dosage. Everyone is different, but the standard dose of 25 mg daily does a good job with most users.

If you look around the bodybuilding circles, you will see that many people have had success with combining Ibutamoren, Candarine and Andarine. Used together, these products form a great cutting stack. A powerful cutting cycle of these three supplements combined would last 10 weeks. You would need to take daily 25 mg of Ibutamoren,  20 mg of Cardarine and 25 mg of Andarine. This is a cycle for more advanced users, but it’s enough to produce a contest worthy level of conditioning, vascularity and leanness.


Side effects of Ibutamoren are few and none. Few if you overdo the drug, either by using it for too long (6 months or longer) or use huge doses. If the instructions I’ve layed out are followed, side effects are rarely an issue.

The only exception can happen for users who are especially prone to prolactin which is less than 1% of people who go on Ibutamoren. Prolactin can basically increase estrogen and lead to symptoms of gynecomastia. However, the chances are rather small. If you’ve used Sustanol or Trenbolone and actually had gynecomastia symptoms occur, than the same could happen with Ibutamoren.

But, I’ll repeat the chances for this are minimal, since both of these drugs are highly anabolic and contain very little androgenic properties. We can view Ibutamoren in the same light. For those that have occuring issues with gynecomastia, it’s always good to have Nolvadex, Arimistane or Clomid at hand.


In conclusion to this extensive article, we can say that Ibutamoren is truly a wonder drug supplement, that we should all be taking advantage of. The price, efficiency and the lack of side effects truly make it worth giving a try.

Whether your goal is to gain muscle and strength, lose fat fast and painlessly and maintain muscle during the cuttin process, or you simply want to improve your overall health and mindset, it’s a one of a kind approach. I hope this article has helped you learn more about Ibutamoren MK-677, and that it will be beneficial in planning a new physique changing cycle.